Multiplex Assays

Many years of development and the expertise of highly qualified scientists from Randox has been invested to create the Biochip Array Technology (BAT) – a multi-analyte testing platform facilitating the simultaneous quantitative or qualitative detection of a wide range of analytes from a single sample. Biochip Array Technology provides a unique platform for assessment of biological samples in a rapid, accurate and easy to use format and users can have the utmost confidence in this proven technology.

 

 

A chemically activated 9x9mm ceramic biochip acts as a solid phase reaction vessel. Biochips are pre-fabricated with discrete test regions (DTR’s); a different antibody/oligonucleotide is immobilised at each spatially distinct DTR. Up to 49 individual DTR’s can be arrayed on to a single biochip with one biochip per sample used to generate multiple results simultaneously. This eliminates the need to run costly, time consuming and sample intensive single analyte assays. The biochip detection is based on a chemiluminescent signal emitting light, without heat, as a result of a chemical reaction. The light emitted is simultaneously detected and quantified using a CCD camera.

 

Adhesion Molecules

Array
E -Selectin
Intercellular Adhesion Molecule-I – ICAM-I
P-Selectin
L-Selectin
Vascular Cell Adhesion Molecule-I – VCAM-I

Acute Kidney Injury

Array
Kidney Injury Molecule - KIM-I
Neutrophil Gelatinase-Associated Lipocalin _ NGAL
Cystatin C
Clusterin
Osteopontin

Alzheimer's

Array
Apolipoprotein E4 - ApoE4
Pan Apolipoprotein E - ApoE

Anaemia

Array
Folate
Vitamin B12

Cardiac

Array
Cardiac Troponin I - cTnI
Creatine Kinase MB - CKMB
Heart Type Fatty Acid Binding Protein - H-FABP
Myoglobin

Cerebral I

Array
Brain-Derived Neurotrophic Factor – BDNF
Glial Fibrillary Acidic Protein – GFAP
Heart-Type Fatty Acid-Binding Protein – H-FABP
Interleukin-6 – IL-6

Cerebral II

Array
C-Reactive Protein - CRP
D-Dimer
Neuron Specific Enolase - NSE
Soluble Tumour Necrosis Factor Receptor I - sTNFR I
Neutrophil Gelatinase-Associated Lipocalin – NGAL

Chronic Kidney Disease I

Array
Fatty Acid Binding Protein-1 – FABP1
Soluble Tumour Necrosis Factor Receptor 1 − sTNFR1
Soluble Tumour Necrosis Factor Receptor 11 − sTNFR 11
Macrophage Inflammatory Protein-1α – MIP-1α
Interleukin-8 – IL-8
Epidermal Growth Factor – EGF
D-Dimer

Chronic Kidney Disease II

Array
Adiponectin
Complement C3a des Arginine – C3a des Arg
C-Reactive Protein – CRP
Neutrophil Gelatinase-Associated Lipocalin – NGAL
Cystatin C

Cytokine I

Array
Interleukin-1 alpha − IL-1α
Interleukin-1 beta − IL-1β
Interleukin-2 − IL-2
Interleukin-4 − IL-4
Interleukin-6 − IL-6
Interleukin-8 − IL-8
Interleukin-10 − IL-10
Vascular Endothelial Growth Factor − VEGF
Epidermal Growth Factor − EGF
Tumour Necrosis Factor-α − TNF-α
Interferon-γ − IFN-γ
Monocyte Chemotactic Protein-1 − MCP-1

Cytokine III

Array
Interleukin-5 − IL-5
Interleukin-15 − IL-15
Granulocyte Macrophage Colony Stimulating Factor – GM-CSF
Macrophage Inflammatory Protein-1α − MIP-1α

Cytokine IV

Array
Matrix Metalloproteinase-9 − MMP-9
Soluble IL 2 Receptor Alpha − sIL-2Rα
Soluble IL 6 Receptor − sIL-6R
Soluble Tumour Necrosis Factor Receptor 1 − sTNFR1
Soluble Tumour Necrosis Factor Receptor 11 − sTNFR 11

Cytokine V

Array
Interleukin-3 − IL-3
Interleukin-7 − IL-7
Interleukin-13 − IL-13
Interleukin-12p70 − IL-12p70
Interleukin-23 − IL-23

Endocrine

Array
Cortisol
Dehydroepiandrosterone-Sulphate – DHEA-S

Fertility

Array
Estradiol
Follicle Stimulating Hormone − FSH
Luteinizing Hormone − LH
Progesterone
Prolactin
Sex Hormone Binding Globulin − SHBG

Gastro

Array
Gastrin 17 − GI7
Pepsinogen I − PGI
Pepsinogen II − PGII

Helicobacter Pylori

Array
Helicobacter pylori – H. pylori

Metabolic Syndrome I

Array
Ferritin
Insulin
Leptin
Plasminogen Activator Inhibitor − PAI-1
Resistin
Interleukin-6 – IL-6
Tumour Necrosis Factor-α – TNF- α

Metabolic Syndrome II

Array
Adiponectin
C-Reactive Protein – CRP
Cystatin C

Stroke

Array
D-Dimer
Glial Fibrillary Acidic Protein − GFAP
Glutathione S – Transferase Pi – GSTPi
Heart-Type Fatty Acid-Binding Protein – H-FABP
Interleukin-6 − IL-6
Nucleoside Diphosphate Kinase – NDKA
Parkinson Protein 7 − PARK-7
Soluble Tumour Necrosis Factor Receptor 1 − sTNFR1

Testosterone

Array
Testosterone

Thyroid Auto Antibody

Array
Anti-Thyroid Peroxidase − Anti-TPO
Anti-Thyroglobulin − Anti-Tg

Thyroid Free

Array
Free Thyroxine − FT4
Free Tri-iodothyronine − FT3
Thyroid Stimulating Hormone − TSH

Thyroid TBG

Array
Thyroxine Binding Globulin − TBG

Thyroid Total

Array
Thyroid Stimulating Hormone − TSH
Total Tri-iodothyronine − TT3
Total Thyroxine − TT4

Tumour PSA

Array
Total Prostate Speci c Antigen – TPSA
Free Prostate Speci c Antigen – FPSA

Vitamin D

Array
Vitamin D